Preparation
These are the things you need to have unlocked:
The Psimultanium pin
Bob's Bottles level
These are things you'll also want to have to make it as quick as possible
The Mental Magnet pin
All the Pyrokinesis badge upgrades
Astral Wallet
Farm The Cash
Head into Bob's brain with your pin(s) equipped. If you haven't beaten this level yet, go inside the first giant bottle on the island the flowers on the water leads to. If you're revisiting, fast travel to Tia's Kitchen.
In the kitchen hallways in this level, use your Pyrokinesis to destroy all the dishes, chairs and other objects scattered around, spawning tons of Psitonium. If your Pyrokinesis is upgraded all the way this should go pretty quick. Also be sure to open the cupboards along the way, as they also include Psitonium.
Continue this process with all 4 kitchens in the level. The last one also have a lot of breakable bottles hidden in the bushes leading down to the battle arena, so if you're revisiting be sure to destroy those too. If this is your original run through the level, going to close to these might trigger a cutscene where you fall down and can't get back until you've beaten the fight down there.
If you have the Psimultanium pin equipped, you should earn around 1000 Psitonium from this! Re-enter the brain and repeat as necessary.
You're Set For Life (or At Least Until Otto Gets It All)!
Source: https://steamcommunity.com/sharedfiles/filedetails/?id=2590029339
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