Setup
Scarlet is the only requirement, runes that increase rate of fire or provide passive shielding are ideal, loyalty is a good idea as you will only need the one summon. Pick any weapon, I like shotgun for good early game damage.
Once in game prioritise ghost friend > best friends > ghost wizard.
Pick up rate of fire upgrades and summon damage while you wait for the first boss, if you're lucky it'll drop the final part of the synergy: Pyromaniac
You're Winner!
Congratulations, for all intents and purposes you've won the run. Now all you need to do is keep your hand off that trigger button.
It works so well i wrote this guide while the game was playing in the background.
Tasty Bonus Synergies
Thunderspawns, hellspawns, and culling work extremely well with this build, as does anything that increases summon damage, fire rate upgrades also stack though are pointless unless you're aiming to stress test your computer.
Best friend means that any on hit effect your bullets would have are also triggered by ghost friend's shots, so dark arts, pyro mage, and frost mage are top tier combos. The latter especially as it stops ranged enemies from shooting and freezes bosses in place while they're torn to shreds.
There are probably more combos that work, it should be noted that effects that trigger from the on-fire or on-reload event (like electro mage or holy arts) are not synergistic with the ghost and so are entirely pointless.
Just throw things at the wall and see what sticks.
Source: https://steamcommunity.com/sharedfiles/filedetails/?id=2907769207
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